2. Signaling Pathways
  3. Antibody-drug Conjugate/ADC Related
  4. ADC Linker
  5. Cleavable Linker Isoform

Cleavable Linker

 

Cleavable Linker Related Products (450):

Cat. No. Product Name Effect Purity
  • HY-20336
    Mc-Val-Cit-PABC-PNP
    		98.89%
    Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs.
  • HY-42973
    DBCO-NHS ester
    		99.53%
    DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
  • HY-78738
    MC-Val-Cit-PAB
    		99.38%
    MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE (HY-15575), which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin.
  • HY-114697
    DSG Crosslinker
    		98.13%
    DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-118759
    DSP Crosslinker
    		98.73%
    DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-78921
    Fmoc-3VVD-OH
    		99.99%
    Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-W000423
    DBCO-amine
    		99.64%
    DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
  • HY-12362
    Val-cit-PAB-OH
    		99.62%
    Val-cit-PAB-OH is a cleavable ADC linker.
  • HY-W000434
    Fmoc-NH-PEG4-CH2CH2COOH
    		99.92%
    Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • HY-44222
    MAC glucuronide linker-2
    		99.38%
    MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-100216
    SPDP
    		≥98.0%
    SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
  • HY-19318
    Fmoc-Val-Cit-PAB
    		99.39%
    Fmoc-Val-Cit-PAB is a cleavable antibody-conjugated active molecule (ADC) commonly used linker.
  • HY-44235
    MC-Gly-Gly-Phe
    		99.05%
    MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
  • HY-42972
    DBCO-acid
    		99.63%
    DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
  • HY-131833
    Fmoc-Gly-Gly-Phe-OH
    		99.49%
    Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • HY-41189
    Fmoc-Val-Cit-PAB-PNP
    		98.99%
    Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers.
  • HY-W007713
    Fmoc-8-amino-3,6-dioxaoctanoic acid
    		99.73%
    Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3,6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • HY-78931
    Boc-Dap-NE
    		99.92%
    Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
  • HY-12448
    SPDB
    		98.82%
    SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).
  • HY-126885
    DBCO-PEG5-NHS ester
    DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.